Primary information |
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ID | antitb_1332, |
Name | 23555622 |
N-Terminal modification | Innate defence regulator peptide 1002 |
C-Terminal Modification | VQRWLIVWRIRK |
Chemical Modification | Free |
Linear/Cyclic | Free |
Length | None |
Chirality | Linear |
Nature | 12 |
Source | L |
Origin | Cationic |
Species | Synthetic |
Inhibition Concentration | Mycobacterium tuberculosis |
In Vitro/ In vivo | Mycobacterium tuberculosis H37Rv |
Cell Line | MIC = 29.3 ± 11.8 mg/mL |
Inhibition Concentration | Both |
Sequence | 2012 |
Cytotoxicity | Human U937 promonocytic cell line |
In vivo Model | NA |
Lethal Dose | None |
Immune Responce | BALB/C |
Mechanism of Action | 32 mg in 100 mL of saline solution (1 mg/kg) |
Target | Increase expression of MCP-1,Gro-α and TNF-α |
Combination Therapy | NA |
Other activities | NA |
PMID | NA |
Year of Publication | Antimicrobial against plasmodium aeruginosa/ S. aureus |
Tertiary Structure (Technique) | Not Predicted), |